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Basic Information
Chinese name : Arbutin (Beta Arbutin)
English name : Arbutin (Beta Arbutin)
Chinese aliases : Arbutin; Arbutin; p-hydroxybenzene-beta-D-glucopyranoside; hydroquinone-beta-D-glucoside; β-arbutin; 4-hydroxybenzene-β-D -Glucopyranoside; Arbutin (β)
CAS RN :497-76-7
EINECS No. 207-850-3
Molecular formula C12H16O7
Molecular weight 272.2512
Physical and chemical properties Melting point 198-201°C
Specific rotation -64° (c=3)
Water solubility 10-15 g/100 mL at 20°C
Functions
Before introducing arbutin, first introduce a substance: hydroquinone. It can interfere with the formation of melanin to achieve a whitening effect, but because of its irritation, it can cause irritant dermatitis and pigmentation, and is listed as a cosmetic ban in many countries. Arbutin introduces a glucose molecule into the molecule, which reduces the irritation, has the ability to interfere with melanocytes and lighten the formed melanin. It has good sun protection ability and strong blemish effect. It is used to treat melasma, freckles and other pigments. Very good efficacy, the limit for use in skin care products is 7%.
Arbutin is mainly extracted from the leaves of Bearberry. Arbutin can also be found in some fruits and other plants. It has the effect of brightening the skin, can quickly penetrate into the skin without affecting the skin cells, and cause melanin The resulting tyrosine combination can effectively block the activity of tyrosinase and the production of melanin, and accelerate the decomposition and elimination of melanin. In addition, arbutin can protect the skin from free radicals and has good hydrophilicity. Therefore, it is often added to commercially available whitening products, and is especially popular in Asian countries.
Arbutin is a natural active substance derived from green plants. It is a skin depigmentation component that combines "green plants, safe and reliable" and "efficient depigmentation". It can quickly penetrate into the skin without affecting cell proliferation. At the same time of concentration, it can effectively inhibit the activity of tyrosinase in the skin, block the formation of melanin, and accelerate the decomposition and excretion of melanin through its direct combination with tyrosinase, thereby reducing skin pigmentation, removing stains and spots. Freckles, and it does not produce toxic, irritating, sensitizing and other side effects on melanocytes, and it also has sterilization and anti-inflammatory effects. It is the safest and most effective whitening material that is popular today, and it is also an ideal skin whitening and freckle active agent in the 21st century.
Applications
Main use: Used in high-end cosmetics, it can be formulated into skin care cream, freckle cream, high-grade pearl cream, etc., which can not only beautify skin care, but also have anti-inflammatory and anti-irritation properties.
Raw materials for burns and scalds: Arbutin is the main component of new-type burns and scalds. It is characterized by rapid pain relief, strong anti-inflammatory effect, rapid elimination of redness and swelling, fast healing, and no scars.
Dosage form: spray or smear.
Raw materials for intestinal anti-inflammatory drugs: good sterilization and anti-inflammatory effects, no toxic side effects.
In fact, the main effect of arbutin is skin lightening to make the skin look youthful and beautiful. The use of arbutin in European and American countries uses this function. As more and more patents expire, arbutin, which was only used in high-end cosmetics in the past, is becoming more and more popular.